Paper Chase is a research database designed to offer abstracts of research articles published in journals that have a highly rated impact factor as determined by ISI Impact Factor and PageRank. Abstracts are organized by date, with the most recently published papers listed first. 

Paper Chase

141.

Health and population effects of rare gene knockouts in adult humans with related parents.

Science.
Narasimhan VM, Hunt KA, Mason D, Baker CL, Karczewski KJ, Barnes MR, Barnett AH, Bates C, Bellary S, Bockett NA, Giorda K, Griffiths CJ, Hemingway H, Jia Z, Kelly MA, Khawaja HA, Lek M, McCarthy S, McEachan R, O'Donnell-Luria A, Paigen K, Parisinos CA, Sheridan E, Southgate L, Tee L, Thomas M, Xue Y, Schnall-Levin M, Petkov PM, Tyler-Smith C, Maher ER, Trembath RC, MacArthur DG, Wright J, Durbin R, van Heel DA.
| Apr 22, 2016
142.

The cellular origins of drug resistance in cancer.

Nat. Med.
Oxnard GR.
| Mar 3, 2016
144.

High-fat diet enhances stemness and tumorigenicity of intestinal progenitors.

Nature.
Beyaz S, Mana MD, Roper J, Kedrin D, Saadatpour A, Hong SJ, Bauer-Rowe KE, Xifaras ME, Akkad A, Arias E, Pinello L, Katz Y, Shinagare S, Abu-Remaileh M, Mihaylova MM, Lamming DW, Dogum R, Guo G, Bell GW, Selig M, Nielsen GP, Gupta N, Ferrone CR, Deshpande V, Yuan GC, Orkin SH, Sabatini DM, Yilmaz ÖH.
| Mar 3, 2016
145.

Stem cells: Dietary fat promotes intestinal dysregulation.

Nature.
Luo C, Puigserver P.
| Mar 3, 2016
146.

Hip Fracture Surgery vs Elective Total Hip Replacement.

JAMA.
Metcalfe D, Perry DC, Costa ML.
| Mar 1, 2016
147.

Screening for Impaired Visual Acuity in Older Adults: US Preventive Services Task Force Recommendation Statement.

JAMA.
Siu AL, Bibbins-Domingo K, Grossman DC, Baumann LC, Davidson KW, Ebell M, García FA, Gillman M, Herzstein J, Kemper AR, Krist AH, Kurth AE, Owens DK, Phillips WR, Phipps MG, Pignone MP.
| Mar 1, 2016
149.

Calcium and Vitamin D for the Prevention of Colorectal Adenomas.

N. Engl. J. Med.
Zhang X, Giovannucci E.
| Feb 25, 2016
150.

Excess Mortality among Persons with Type 2 Diabetes.

N. Engl. J. Med.
Zhang Y, Niu J, Choi HK.
| Feb 25, 2016
151.

CASE RECORDS of the MASSACHUSETTS GENERAL HOSPITAL. Case 6-2016. A 10-Year-Old Boy with Abdominal Cramping and Fevers.

N. Engl. J. Med.
Biller JA, Butros SR, Chan-Smutko G, Abrams AN, Chung DC, Hagen CE.
| Feb 25, 2016
152.

Weekly vs. Every-3-Week Paclitaxel and Carboplatin for Ovarian Cancer.

N. Engl. J. Med.
Chan JK, Brady MF, Penson RT, Huang H, Birrer MJ, Walker JL, DiSilvestro PA, Rubin SC, Martin LP, Davidson SA, Huh WK, O'Malley DM, Boente MP, Michael H, Monk BJ.
| Feb 25, 2016
153.

Structure of an endogenous yeast 26S proteasome reveals two major conformational states.

Proc. Natl. Acad. Sci. U.S.A.
Luan B, Huang X, Wu J, Mei Z, Wang Y, Xue X, Yan C, Wang J, Finley DJ, Shi Y, Wang F.
| Mar 8, 2016
154.

Type VI secretion system sheaths as nanoparticles for antigen display.

Proc. Natl. Acad. Sci. U.S.A.
Del Tordello E, Danilchanka O, McCluskey AJ, Mekalanos JJ.
| Feb 29, 2016
155.

Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations.

Nat. Genet.
Bueno R, Stawiski EW, Goldstein LD, Durinck S, De Rienzo A, Modrusan Z, Gnad F, Nguyen TT, Jaiswal BS, Chirieac LR, Sciaranghella D, Dao N, Gustafson CE, Munir KJ, Hackney JA, Chaudhuri A, Gupta R, Guillory J, Toy K, Ha C, Chen YJ, Stinson J, Chaudhuri S, Zhang N, Wu TD, Sugarbaker DJ, de Sauvage FJ, Richards WG, Seshagiri S.
| 02 29, 2016
156.

Clinical Genomics: From Pathogenicity Claims to Quantitative Risk Estimates.

JAMA.
Manrai AK, Ioannidis JP, Kohane IS.
| 3 2, 2016
157.

Exploiting Temporal Collateral Sensitivity in Tumor Clonal Evolution.

Cell.
Zhao B, Sedlak JC, Srinivas R, Creixell P, Pritchard JR, Tidor B, Lauffenburger DA, Hemann MT.
| Mar 24, 2016
158.

Cytotoxic T Cells Use Mechanical Force to Potentiate Target Cell Killing.

Cell.
Basu R, Whitlock BM, Husson J, Le Floc'h A, Jin W, Oyler-Yaniv A, Dotiwala F, Giannone G, Hivroz C, Biais N, Lieberman J, Kam LC, Huse M.
| Mar 24, 2016
160.

EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection.

Cell.
Olenchock BA, Moslehi J, Baik AH, Davidson SM, Williams J, Gibson WJ, Pierce KA, Miller CM, Hanse EA, Kelekar A, Sullivan LB, Wagers AJ, Clish CB, Vander Heiden MG, Kaelin WG.
| Feb 25, 2016