Paper Chase is a research database designed to offer abstracts of research articles published in journals that have a highly rated impact factor as determined by ISI Impact Factor and PageRank. Abstracts are organized by date, with the most recently published papers listed first. 

Paper Chase

1.

Structure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G.

Proc. Natl. Acad. Sci. U.S.A.
Papadopoulos E, Jenni S, Kabha E, Takrouri KJ, Yi T, Salvi N, Luna RE, Gavathiotis E, Mahalingam P, Arthanari H, Rodriguez-Mias R, Yefidoff-Freedman R, Aktas BH, Chorev M, Halperin JA, Wagner G.
| Jul 21, 2014
2.

Phosphatidylinositol 4,5-bisphosphate triggers activation of focal adhesion kinase by inducing clustering and conformational changes.

Proc. Natl. Acad. Sci. U.S.A.
Goñi GM, Epifano C, Boskovic J, Camacho-Artacho M, Zhou J, Bronowska A, Martín MT, Eck MJ, Kremer L, Gräter F, Gervasio FL, Perez-Moreno M, Lietha D.
| Jul 21, 2014
3.

Next-generation sequencing identifies rare variants associated with Noonan syndrome.

Proc. Natl. Acad. Sci. U.S.A.
Chen PC, Yin J, Yu HW, Yuan T, Fernandez M, Yung CK, Trinh QM, Peltekova VD, Reid JG, Tworog-Dube E, Morgan MB, Muzny DM, Stein L, McPherson JD, Roberts AE, Gibbs RA, Neel BG, Kucherlapati R.
| Jul 21, 2014
4.

Denervation protects limbs from inflammatory arthritis via an impact on the microvasculature.

Proc. Natl. Acad. Sci. U.S.A.
Stangenberg L, Burzyn D, Binstadt BA, Weissleder R, Mahmood U, Benoist C, Mathis D.
| Jul 21, 2014
5.

Prolactin prevents hepatocellular carcinoma by restricting innate immune activation of c-Myc in mice.

Proc. Natl. Acad. Sci. U.S.A.
Hartwell HJ, Petrosky KY, Fox JG, Horseman ND, Rogers AB.
| Jul 21, 2014
6.

Writing well: lowering the barriers to success.

Nat. Immunol.
Gould JC, Luna RE, Vogel DL.
| Jul 21, 2014
7.

Tumour-derived PTH-related protein triggers adipose tissue browning and cancer cachexia.

Nature.
Kir S, White JP, Kleiner S, Kazak L, Cohen P, Baracos VE, Spiegelman BM.
| Jul 13, 2014
8.

Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer.

Nature.
Saha SK, Parachoniak CA, Ghanta KS, Fitamant J, Ross KN, Najem MS, Gurumurthy S, Akbay EA, Sia D, Cornella H, Miltiadous O, Walesky C, Deshpande V, Zhu AX, Hezel AF, Yen KE, Straley KS, Travins J, Popovici-Muller J, Gliser C, Ferrone CR, Apte U, Llovet JM, Wong KK, Ramaswamy S, Bardeesy N.
| Jul 2, 2014
9.

Histone H4 tail mediates allosteric regulation of nucleosome remodelling by linker DNA.

Nature.
Hwang WL, Deindl S, Harada BT, Zhuang X.
| Jun 29, 2014
10.

Targeting transcription regulation in cancer with a covalent CDK7 inhibitor.

Nature.
Kwiatkowski N, Zhang T, Rahl PB, Abraham BJ, Reddy J, Ficarro SB, Dastur A, Amzallag A, Ramaswamy S, Tesar B, Jenkins CE, Hannett NM, McMillin D, Sanda T, Sim T, Kim ND, Look T, Mitsiades CS, Weng AP, Brown JR, Benes CH, Marto JA, Young RA, Gray NS.
| Jun 22, 2014
11.

Structure of the DDB1-CRBN E3 ubiquitin ligase in complex with thalidomide.

Nature.
Fischer ES, Böhm K, Lydeard JR, Yang H, Stadler MB, Cavadini S, Nagel J, Serluca F, Acker V, Lingaraju GM, Tichkule RB, Schebesta M, Forrester WC, Schirle M, Hassiepen U, Ottl J, Hild M, Beckwith RE, Harper JW, Jenkins JL, Thomä NH.
| Jul 16, 2014
12.

Loss of oncogenic Notch1 with resistance to a PI3K inhibitor in T-cell leukaemia.

Nature.
Dail M, Wong J, Lawrence J, O'Connor D, Nakitandwe J, Chen SC, Xu J, Lee LB, Akagi K, Li Q, Aster JC, Pear WS, Downing JR, Sampath D, Shannon K.
| Jul 20, 2014
13.

Rapid seeding of the viral reservoir prior to SIV viraemia in rhesus monkeys.

Nature.
Whitney JB, Hill AL, Sanisetty S, Penaloza-MacMaster P, Liu J, Shetty M, Parenteau L, Cabral C, Shields J, Blackmore S, Smith JY, Brinkman AL, Peter LE, Mathew SI, Smith KM, Borducchi EN, Rosenbloom DI, Lewis MG, Hattersley J, Li B, Hesselgesser J, Geleziunas R, Robb ML, Kim JH, Michael NL, Barouch DH.
| Jul 20, 2014
14.

Hypertension in populations of different ethnic origins.

Lancet.
Dhillon RS, Clair K, Fraden M, Abdalla M.
| Jul 19, 2014
15.

Most genetic risk for autism resides with common variation.

Nat. Genet.
Gaugler T, Klei L, Sanders SJ, Bodea CA, Goldberg AP, Lee AB, Mahajan M, Manaa D, Pawitan Y, Reichert J, Ripke S, Sandin S, Sklar P, Svantesson O, Reichenberg A, Hultman CM, Devlin B, Roeder K, Buxbaum JD.
| Jul 20, 2014
16.

Evaluating a multipayer medical home intervention.

JAMA.
Cronholm PF, Miller-Day M, Gabbay R.
| Jul 23, 2014
17.

HIV Prevention in Clinical Care Settings: 2014 Recommendations of the International Antiviral Society-USA Panel.

JAMA.
Marrazzo JM, Del Rio C, Holtgrave DR, Cohen MS, Kalichman SC, Mayer KH, Montaner JS, Wheeler DP, Grant RM, Grinsztejn B, Kumarasamy N, Shoptaw S, Walensky RP, Dabis F, Sugarman J, Benson CA.
| Jul 23, 2014
18.

Effect of Tesamorelin on Visceral Fat and Liver Fat in HIV-Infected Patients With Abdominal Fat Accumulation: A Randomized Clinical Trial.

JAMA.
Stanley TL, Feldpausch MN, Oh J, Branch KL, Lee H, Torriani M, Grinspoon SK.
| Jul 23, 2014
19.

Pregnancy Incidence and Outcomes Among Women Receiving Preexposure Prophylaxis for HIV Prevention: A Randomized Clinical Trial.

JAMA.
Mugo NR, Hong T, Celum C, Donnell D, Bukusi EA, John-Stewart G, Wangisi J, Were E, Heffron R, Matthews LT, Morrison S, Ngure K, Baeten JM.
| Jul 23, 2014
20.

SnapShot: Necroptosis.

Cell.
Zhou W, Yuan J.
| Jul 17, 2014