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What is Cystic Fibrosis?

Cystic fibrosis is an inherited disorder that affects many organs in the body, including the lungs, liver, pancreas, and reproductive tract. Specific cells in these organs normally produce mucus and other watery secretions. In cystic fibrosis, these cells produce secretions that are thicker than normal, causing disruptions in the body's water balance. This creates other problems. For example, in the lungs, thickened secretions trap germs, causing repeated lung infections. In the pancreas, thickened secretions block the normal flow of pancreatic juices, making it more difficult for the body to digest and absorb fats. This can result in nutritional problems, especially in babies. For information on symptoms, diagnosis, and treatment click here.
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Research News

Featuring Harvard Medical School and Affiliated Hospitals

Discovery Could Aid Fight Against Cystic Fibrosis Researchers have discovered one way that a bacteria could be surviving in the lungs of infected cystic fibrosis patients.

Cystic Fibrosis Gene Linked to Fatty Acid Defects Discovery could pave the way for a new treatment.

Researchers Discover Potential New Approach to Treating Cystic Fibrosis Researchers say they have discovered a reversible lipid imbalance that may be responsible for the common symptoms of cystic fibrosis.

Research Stories

From the Harvard University Gazette

Novel MRI Technology May Shed New Light on Treatment of Asthma, Cystic Fibrosis, and Emphysema
Noninvasive and safe technique produces clear and accurate 3-D images of the lungs.

>More HU Gazette on Cystic Fibrosis

Scientific Reports

From HMS Faculty Newsletter Focus

Fatty-acid Imbalance May Boost Inflammation in CF
It now appears that the cystic fibrosis mutant gene may cause disease by altering the balance of another set of primordial molecules, the fatty acids.

Lung Imaging Method Allows Visualization of Airways Technology will open new venues in research on lung diseases by creating clear images.

>More Research Reports

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Last updated June 2006
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