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What are HIV and AIDS?

HIV (human immunodeficiency virus) weakens the body's immune defenses by destroying CD4 (T-cell) lymphocytes. CD4 lymphocytes are a group of white blood cells that normally help guard against attacks by bacteria, viruses, and other germs by coordinating the immune system. When HIV destroys CD4 lymphocytes, the body becomes vulnerable to many different types of opportunistic infections that invade the body because its immune defenses are weak. The entire spectrum of symptoms and illnesses that can happen when HIV infection significantly depletes immune defenses is called AIDS (acquired immunodeficiency syndrome). For information on symptoms, diagnosis, and prevention click here.

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Research News

Featuring HMS and Affiliated Hospitals

Novel Genetics Research advances possibility of HIV vaccine.

HIV Infection Appears to increase the risk of heart attack.

Effective HIV Control may depend on which viral protein is targeted.

HIV and Hepatits C Study examines impact of infection with both.

Inherited Factors may affect early-stage immune system control.

The Mystery of Natural HIV Control Study will examine genetics and immune systems.

AIDS Vaccine Research Offers New Insights Subpopulation of T-cells provides immunity and promotes survival.

Study offers new hope for preventive vaccine.

Novel Candidate Vaccine Vector Reported

Elusive HIV Shape Change Revealed
Key clue to how virus infects cells.

Study Finds Protein Can Drive Immune Cells Away

Natural Blocker of HIV-1 Virus Researchers have identified a protein in monkeys that blocks infection by HIV-1.

>More Research News

Research Stories

From the Harvard University Gazette

Battling AIDS in Brazil:
A message of hope.

Exercise Boosts Health of HIV-infected Women
Dramatic physical, mental improvement seen.

Study: Hope Alive for AIDS Vaccine

HSPH Finds AIDS Drugs Work Well in Botswana
Regime effective without extensive health infrastructure.

New AIDS Vaccine Tested in U.S., Africa
Tests of a new vaccine against the AIDS virus are being launched simulta-neously in the United States and southern Africa.

>More HU Gazette

Scientific Reports

From HMS Faculty Newsletter Focus

Sugar Receptor on brain immune cells gums up viral infection.

Drug Can Protect Mothers and Babies
New study examines timing of dosage.

Masked Vector Rides Past Immune Defense
Tested in animals, chimeric vaccine carrier heads toward clinical trial.

Brain Injury Reversed in Animal Model
Damage from other disorders may also be reversible.

AIDS and Isolation Among the Navajo

Genetic Battleground Marked between HIV and host.

Prevention May Double Effectiveness of global HIV/AIDS treatment.

Multivitamins Can Delay Onset of AIDS Results of an eight-year study look promising.

Priming Cellular Pathway May Lead To New Vaccines Dendritic cells could be turned toward smarter T cell activation.

>More Research Reports

©The President and Fellows of Harvard College
Last updated August 2007
Photo collage from the US Office of HIV/AIDS Policy