Tools and Technology

Tools and Technology at HMS

Technology may be the single most important driver of discovery in biomedical science.

The Tools and Technology Committee (TnT) was created to ensure that HMS achieves and maintains world leadership in critical areas of biomedical research. TnT program funds help support and expand our shared facilities and technologies on the quad and help drive new programs in technology innovations and development.

Read the Tools & Technology Committee Report


TnT Funding Opportunities

The TnT Program funds upgrade and equipment purchases for existing cores, the purchase of shared equipment made available within departments, and the start-up costs for new core facilities. The TnT Committee is working closely with departments and department leadership to identify future funding opportunities and needs. Stay tuned for more information about upcoming funding opportunities.

Featured: Recently Supported Programs

Centralized Mechanism for Scientific Software Support
SBGrid currently supports the structural biology community by collecting, maintaining, and installing the scientific software necessary for research. TnT funding will allow us to expand this service to other disciplines throughout Harvard Medical School. In the first stage of this activity, a comprehensive collection of scientific software supported by SBGrid will be made accessible to all members of the HMS community on the RITG Orchestra Cluster. Access to software collection will be extended to scientific workstations at HMS laboratories as the project develops.
Visit the Core's website.

Genome Engineering Production Group
The Genome Engineering Production Group (GEPG) was established in 2013 with the goal of facilitating genome engineering-based research through the availability of reasonably priced tools. The GEPG currently offers custom TALEN and CRISPR nuclease constructs for use in engineering human and mouse cells, as well as for model organisms including zebrafish, C. elegans, and Drosophila.  We also offer TALE-based transcriptional activator constructs.
Visit the core's website.

See the complete list of TnT Funded Proposals.


To support and stimulate the development and dissemination of tools and technologies to ensure that HMS maintains world leadership in critical areas of biomedical research.

TnT Committee


Stephen Harrison, PhD, Chair
Professor, Department of Biological Chemistry and Molecular Pharmacology


Judith Glaven, PhD
Associate Dean for Basic and Interdisciplinary Research


Robert Datta, MD, PhD
Assistant Professor, Department of Neurobiology


Wade Harper, PhD
Professor, Department of Cell Biology


Norbert Perrimon, PhD
Professor, Department of Genetics


Michael Springer, PhD
Assistant Professor, Department of Systems Biology


Suzanne Walker, PhD
Professor, Department of Microbiology and Immunobiology


Christopher Botka, IT Advisor to Committee
Chief Technology Officer